- PII
- S30346304S0514749225030136-1
- DOI
- 10.7868/S3034630425030136
- Publication type
- Article
- Status
- Published
- Authors
- Volume/ Edition
- Volume 61 / Issue number 3
- Pages
- 322-328
- Abstract
- Imidazolin-4-one derivatives have been prepared by a reaction of ethyl [cyano(4,6-dimethylpyrimidin-2-yl)amino]acetate (2) with morpholine, piperidine and hydrazides. In the presence of sulfuric acid, cyanoester 2 gives 2-iminooxazolin-5-one which is acylated on the nitrogen atom of imino group and is rearranged to imidzolidin-2,4-dione in the presence of KCNO.
- Keywords
- пиримидин имидазол оксазол этилхлорацетат цианамид циклизация
- Date of publication
- 25.12.2024
- Year of publication
- 2024
- Number of purchasers
- 0
- Views
- 18
References
- 1. Thakur A., Verma M., Bharti R., Sharma R. Tetrahedron. 2022, 119, 132813. doi 10.1016/j.tet.2022.132813
- 2. Joshi S., Mehra M., Singh R., Kakar S. Egypt. J. Basic Appl. Sci. 2023, 10, 1, 218-239. doi 10.1080/2314808X.2023.2171578
- 3. Kushwaha N., Kushwaha S. Biointerface Res. Appl. Chem. 2022, 12, 5, 6460-6486. doi 10.33263/BRIAC125.64606486
- 4. Rulhania S., Kumar S., Nehra B., Gupta G.D., Monga V. J. Mol. Struct. 2021, 1232, 129982. doi 10.1016/j.molstruc.2021.129982
- 5. Alghamdi S.S., Suliman R.S., Almutairi K., Kahtani K., Aljatli D. Drug Design Develop. Ther. 2021, 15, 3289-3312. doi 10.2147/DDDT.S307113
- 6. Siwach A., Verma P.K. BMC Chem. 2021, 15, 12, 1-69. doi 10.1186/s13065-020-00730-1
- 7. Gujjarappa R., Kabi A.K., Sravani S., Garg A., Vodnala N., Tyagi U., Kaldhi D., Velayutham R., Singh V., Gupta S. Overview on Biological Activities of Imidazole Derivatives. Ed. B.P. Swain. Singapore: Springer. Publ. 2022, 135-227. doi 10.1007/978-981-16-8399-2_7
- 8. Gujjarappa R., Sravani S., Kabi A.K., Garg A., Vodnala N., Tyagi U., Kaldhi D., Singh V., Gupta S., Malakar C.C. An Overview on Biological Activities of Oxazole, Isoxazoles and 1,2,4-Oxadiazoles Derivatives. Ed. B.P. Swain. Singapore: Springer. Publ. 2022, 379-400. doi 10.1007/978-981-16-8399-2_10
- 9. Tolomeu H.V., Fraga C.A.M. Molecules 2023, 28, 838. doi 10.3390/molecules28020838
- 10. Sharma P., LaRosa C., Antwi J., Govindarajan R., Werbovetz K.A. Molecules 2021, 26, 4213. doi 10.3390/molecules26144213
- 11. Guerrero-Pepinosa N.Y., Cardona-Trujillo M.C., Garzґon-Casta˜no S.C., Veloza L.A., Sepúlveda-Arias J.C. Biomed. Pharmacother. 2021, 138, 111495. doi 10.1016/j.biopha.2021.111495
- 12. Albayatia M.R., Mohamed M.F.A., Moustafa A.H. Synth. Commun. 2020, 50, 8, 1217-1231. doi 10.1080/00397911.2020.1735443
- 13. Moustafa A.H., Ahmed W.W., Awad M.F., Aboelez M.O., Khodairy A., Amer A.A. Mol. Div. 2022, 26, 2813-2823. doi 10.1007/s11030-022-10401-z
- 14. Dovlatyan V.V., Eliazyan K.A., Pivazyan V.A. Chem. Heterocycl. Compd. 1994, 30 (9), 1074-1076. doi 10.1007/BF01171168
- 15. Shestakov A.S., Moustafa A.H., Bushmarinov I.S., Goloveshkin A.S., Shapovalov A.V., Shikhaliev K.S., Prezent M.A., Sidorenko O.E. J. Heterocycl. Chem. 2017, 54, 551-560. doi 10.1002/jhet.2621
- 16. Fodor G., Koczka K. J. Chem. Soc. 1952, 850-854. doi 10.1039/JR9520000850
- 17. Dutta S., Higginson C.J., Ho B.T., Rynearson K.D., Dibrov S.M., Hermann T. Org. Lett. 2010, 12 (2), 360-363. doi 10.1021/ol9026914
- 18. Dutta S., Dibrov S.M., Ho B.T., Higginson C.J., Hermann T. J. Chem. Crystallogr. 2012, 42, 119-129. doi 10.1007/s10870-011-0212-6
- 19. Basavaprabhu H., Sureshbabu V.V. Org. Biomol. Chem. 2012, 10 (13), 2528-2533. doi 10.1039/c2ob06916d
- 20. Wildermuth R.E., Steinborn C., Barber D.M., Muhlfenzl K.S., Kendlbacher M., Mayer P., Wurst K., Magauer T. Chem. Eur. J. 2021, 27, 12181-12189. doi 10.1002/chem.202101849
- 21. Steinborn C., Wildermuth R.E., Barber D.M., Magauer T. Angew. Chem. Int. Ed. 2020, 59, 17282-17285. doi 10.1002/anie.202008158
- 22. Masumoto E., Maruoka H., Okabe F., Fujioka T., Yamagata K. J. Heterocycl. Chem. 2015, 52, 48-53. doi 10.1002/jhet.1946
- 23. Birtwell S. J. Chem. Soc. 1953, 1725-1730. doi 10.1039/JR9530001725