- PII
- S30346304S0514749225050072-1
- DOI
- 10.7868/S3034630425050072
- Publication type
- Article
- Status
- Published
- Authors
- Volume/ Edition
- Volume 61 / Issue number 5
- Pages
- 566-571
- Abstract
- Starting from (±)-lactonediol Corey, a practical route for the synthesis of (±)-Entecavir was developed, the key step of which is the preparation of (1R*,3R*,4S*)-4-(1-ethoxyethoxy)-3-[(1-ethoxyethoxy)methyl]-2-methylenecyclopentanol by oxidative decarboxylation of {(1S*,2R*,3S*,5R*)-5-{[tert-butyl(dimethyl)silyl]oxy}-3-(1-ethoxyethoxy)-2-[(1-ethoxyethoxy)methyl]cyclopentyl}acetic acid with lead tetraacetate.
- Keywords
- лактондиол Кори экзометиленциклопентанолы 2-амино-6-хлорпурин реакция Мицунобу синтез карбонуклеозиды энтекавир
- Date of publication
- 12.12.2025
- Year of publication
- 2025
- Number of purchasers
- 0
- Views
- 47
References
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